GHS hazard statement
H281
Contains refrigerated gas; may cause cryogenic burns or injury
GHS04 · Gas cylinder- Hazard group
- Physical hazards
- Hazard class
- Gas under pressure (refrigerated)
- Signal word
- Danger
What H281 means
H281 is the GHS (Globally Harmonized System) hazard statement “Contains refrigerated gas; may cause cryogenic burns or injury.” It belongs to the Gas under pressure (refrigerated) hazard class and appears in Section 2 of a Safety Data Sheet and on the product label when a substance or mixture meets the classification criteria for that class and category.
Where H281 applies, GHS assigns the signal word Danger and the GHS04 (Gas cylinder) pictogram. The exact signal word and pictogram set on a finished label come from the whole classification — the most severe endpoint drives the signal word, so a milder statement can be present without changing an already-Danger label.
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Reference information, not a compliance determination. Actual label elements depend on the full classification of your specific substance or mixture and require review by a qualified professional.